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CharacteristicsPassage 2 or 3 — Passage 1 on request — Single Donor
ApplicationsAngiogenesis — Inflammation — Oncology — Vascular Biology
Human Umbilical Vein Endothelial Cells (HUVECs)
Human Umbilical Vein Endothelial Cells (HUVECs) are mature endothelial cells isolated from the umbilical cord vein. These cells present a typical cobblestone morphology. They provide a classic model system to study multiple aspects of endothelial function and disease, such as normal and tumor-associated angiogenesis, oxidative stress, hypoxia and inflammation related pathways and mechanisms of action studies for cardiovascular-related diseases.
Abcell-bio offers mature endothelial cells isolated from human umbilical cord vein.
These adherent cells express all the specific markers of endothelial cells: CD31, CD144 and KDR, and vWF factor. Our HUVECs are derived from a single, healthy donor.
HUVEC cells are tested for the specific markers of endothelial cells, such as CD31, CD144, KDR and vWF. The expression of these markers is analyzed by Flow Cytometry and Immunohistochemical Labeling. Abcell-bio evaluates the specific endothelial functions of each batch of HUVECs, such as the ability to incorporate acetylated LDL or the potential expression of activation molecules (ICAM-1, VCAM-1). These cells are able to form capillary-like structures on Matrigel®, reflecting their angiogenic capacity.
HUVECs produced by Abcell-bio are cryopreserved in FBS-10% DMSO and provided at passage 2 ou 3 after thawing (passage 1 on request). Virologic (HIV1/2, HBV, HCV) and mycoplasma detection tests are performed on all batches. A full certificate of analysis is provided for each batch of HUVEC cells ordered.
Order customization on request
Early passage, specific batch size